The Interior — Medicine and HealthGrades 3–5

Unit 5 · Germs, Vaccines and First Aid

Start with the story. Then go through each chapter, one lesson at a time. Each lesson has three short checks. Each chapter ends with a review. The unit ends with a wrap-up.

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5Unit

Germs, Vaccines and First Aid

Staying Well

Every day, your body meets germs too small to see. Most of the time, you never notice. Your skin, your immune system and simple habits like handwashing keep you well. Sometimes a germ gets through, and you catch a cold or a fever.

People have learned a lot about germs over hundreds of years. A country doctor named Edward Jenner made the first vaccine. Scientists found antibiotics. Health workers around the world worked together to wipe out smallpox.

In this unit, you will learn how germs spread and how your body fights back. You will also learn first aid for small hurts, when to call 911, and how to stay calm and get a trusted adult. You can be a real helper.

When it happened
c. 1670s

Antonie van Leeuwenhoek sees tiny living things through his handmade microscopes.

1796

Edward Jenner uses cowpox to protect James Phipps from smallpox.

1798

Jenner publishes his report on cowpox and smallpox.

1881

Clara Barton founds the American Red Cross.

1928

Alexander Fleming notices mold killing bacteria; this leads to penicillin.

1940s

Penicillin is made in large amounts and saves many lives.

1967

The World Health Organization begins its big push to end smallpox.

1968

The first 911 call in the United States is made, in Alabama.

1977

The last natural case of smallpox is found, in Somalia.

1980

Smallpox is declared eradicated, the first human disease wiped out.

Chapter

Germs and How We Fight Them

Germs
Big questionGerms are too small to see, so how do our bodies, our habits and our medicines keep us well?
The story

The Milkmaid's Clear Skin

An old country story helped a doctor find a way to stop one of the worst sicknesses in history.

Long ago in the English countryside, a sickness called smallpox scared almost everyone. It gave people a high fever and bumpy spots all over the skin. Many people died from it. Many who got well had scars on their faces for life.

Edward Jenner was a country doctor in the village of Berkeley, England. Farm families there told an old story. They said milkmaids who caught a mild sickness from cows almost never got smallpox. That cow sickness was called cowpox. It gave a milkmaid a few sores on her hands, and then she got well.

One well-known telling says a young milkmaid spoke to Jenner herself. She said she would never catch smallpox, because she had already had cowpox. Nobody knows her exact words. But Jenner kept thinking about the idea. Could a mild cow sickness protect a person from a deadly one?

In 1796 Jenner decided to test it. He took a little matter from a cowpox sore on the hand of a milkmaid named Sarah Nelmes. He put it into a small cut on the arm of an eight-year-old boy, James Phipps. James got a little sick and then got better.

Weeks later, Jenner exposed James to smallpox. James did not get sick. Jenner tested more people and wrote down what he saw. His work led to the first vaccine. Doctors today would never test on a child that way, but his idea changed the world.

Talk about itJenner heard a story, then tested it. Why is it important to test an idea instead of just believing a story?
Section 1

Meet the Germs

9.1

Bacteria Are Tiny Living Things

Main ideaBacteria are tiny one-celled living things; most are harmless or helpful, but a few can make us sick.

Think about a spoonful of yogurt. It is full of living things, too small to see. They are called . Each one is just a single cell. You would need a microscope to see them.

Bacteria live almost everywhere. They live in soil, in water and on your skin. Millions live inside your gut. Most bacteria do not hurt you. Many help you digest food or turn milk into yogurt.

A few kinds of bacteria are . A germ is a tiny living thing that can make you sick. One kind of bacteria causes strep throat. Another kind can get into a cut and make it red and sore.

Words to know
bacteria
tiny living things made of just one cell; most are harmless, and a few cause sickness
germs
tiny living things, like some bacteria and viruses, that can make you sick
Check yourself

1. What are bacteria?

2. Which is true about most bacteria?

3. Which sickness is caused by a kind of bacteria?

9.2

Viruses Need a Host

Main ideaViruses are even smaller than bacteria, and they can only make more of themselves inside a living cell.

When you catch a cold, a is usually the cause. A virus is a germ even smaller than bacteria. The flu and chickenpox are also caused by viruses.

A virus cannot grow or make copies on its own. It must get inside a living cell. The cell it uses is called the . Inside, the virus makes the cell build many new viruses. Then they spread to more cells.

Bacteria and viruses are both germs, but they are different. Bacteria are living cells. Viruses are much smaller and are not cells at all. This difference matters when doctors choose a medicine.

Words to know
virus
a very tiny germ that can only make copies of itself inside a living cell
host
the living thing or cell that a virus uses to make copies of itself
Check yourself

1. What must a virus do to make copies of itself?

2. Which is usually caused by a virus?

3. How are viruses different from bacteria?

9.3

How Germs Travel

Main ideaGerms spread through the air, by touch, and in food and water, so washing hands and covering coughs help.

Maya sneezes into the air. Tiny drops fly out. If she has a cold, the drops carry the virus. A friend nearby can breathe them in. That is one way germs .

Germs also spread by touch. Someone coughs into a hand, then touches a door handle. The next person touches it and then rubs an eye. Germs can also ride in food that was not cooked well, or in dirty water.

Simple habits block these paths. Wash hands with soap and water for about 20 seconds. Cough or sneeze into your elbow. Keep food clean and cooked. Drink clean water. These habits cut down the chances of getting sick. This is called good .

Words to know
spread
to pass from one person or place to another
hygiene
habits that keep you and others clean and healthy, like washing hands
Check yourself

1. Which is one way germs spread?

2. How long should you scrub hands with soap?

3. Where is the best place to sneeze if you have no tissue?

Section 2

Your Body Fights Back

9.4

White Blood Cells on Guard

Main ideaThe immune system uses white blood cells to find and destroy germs that get into the body.

Your skin is like a wall that keeps most germs out. But sometimes germs get in, like through a scrape on your knee. Then your body has a team ready to fight. That team is your .

The fighters are . They travel in your blood to where germs are. Some white blood cells swallow germs whole. Others make . Antibodies are like tags that stick to a germ so other cells can find it and destroy it.

Your immune system also remembers. After it beats a germ, some cells keep a memory of it. If the same germ comes back, your body can fight it faster. This memory is why many people get chickenpox only once.

Words to know
immune system
the body's team of cells and organs that fights germs
white blood cells
blood cells that find and fight germs
antibodies
tiny tags the body makes that stick to one kind of germ so it can be destroyed
Check yourself

1. What is the job of white blood cells?

2. What do antibodies do?

3. Why do many people get chickenpox only once?

9.5

A Fever Is a Fight

Main ideaA fever is a higher body temperature that often means the immune system is fighting germs.

Ana wakes up hot and tired. Her dad checks her with a thermometer. Her temperature is higher than usual. She has a . Her dad tucks her back into bed with a glass of water.

A fever is not a germ. It is one way your body fights germs. When germs get in, the body turns up its heat. Some germs do not grow as well in a warmer body. The heat may also help the immune system work.

A fever can make you feel tired and achy. Resting and drinking water help. Tell a grown-up when you feel hot or sick. A grown-up can check your and call a doctor or nurse if needed.

Words to know
fever
a body temperature higher than usual, often a sign the body is fighting germs
temperature
how hot or cold something is, measured with a thermometer
Check yourself

1. What is a fever?

2. How can a fever help the body?

3. What should Ana do when she feels hot and sick?

Section 3

Vaccines Teach the Body

9.6

How a Vaccine Works

Main ideaA vaccine teaches the immune system to know a germ, so the body is ready before the real germ arrives.

A fire drill helps you practice before there is a real fire. A is like a drill for your immune system. It lets the body practice fighting a germ without getting very sick.

A vaccine holds a weak, dead or harmless piece of a germ, or instructions for making one. It is often given as a shot. The immune system sees it and makes antibodies. It also makes memory cells.

Later, the real germ may come. Now the body knows it. It can fight fast, often before you feel sick. This protection is called . Your doctor or nurse can tell you which vaccines you need and when.

Words to know
vaccine
a medicine, often a shot, that teaches the immune system to know a germ
immunity
the body's protection against a germ it already knows
Check yourself

1. What does a vaccine do?

2. What does a vaccine usually hold?

3. What is immunity?

9.7

Edward Jenner Tests an Idea

Main ideaIn 1796 Edward Jenner used cowpox to protect a boy from smallpox, which led to the first vaccine.

was a sickness caused by a virus. It killed many people for thousands of years. In the 1700s, English farm families noticed something. Milkmaids who had caught from cows seemed safe from smallpox.

Edward Jenner, a country doctor, tested this idea in 1796. He put matter from a cowpox sore into a cut on James Phipps’s arm. Later, he exposed James to smallpox. James stayed well.

Jenner wrote a book about his tests in 1798. The word vaccine comes from vacca, the Latin word for cow. Today, doctors test vaccines with careful rules to keep volunteers safe.

Words to know
smallpox
a deadly sickness caused by a virus that gave people fever and spots
cowpox
a mild sickness from cows that protected people from smallpox
Check yourself

1. What did Jenner use to protect James Phipps?

2. When did Jenner test his idea on James?

3. Where does the word vaccine come from?

9.8

The End of Smallpox

Main ideaVaccines used all over the world wiped out smallpox, and in 1980 it was declared gone.

After Jenner, many countries began to vaccinate people against smallpox. In 1967 the World Health Organization started a big push to end it everywhere. Health workers traveled to villages all over the world.

The workers found each new case. Then they vaccinated everyone around that sick person. This stopped the virus from finding new people. The last natural case was found in Somalia, in Africa, in 1977.

In 1980 the World Health Organization said smallpox was . That means it was wiped out in the wild. It is the first human disease ever wiped out. It took teamwork from many .

Words to know
eradicated
wiped out completely, so it no longer spreads anywhere
nations
countries with their own governments
Check yourself

1. What does eradicated mean?

2. In what year was smallpox declared gone?

3. How did health workers stop smallpox from spreading?

Section 4

Medicines for Germs

9.9

Antibiotics Fight Bacteria

Main ideaAntibiotics are medicines that kill bacteria or stop them from growing.

In 1928, a scientist named Alexander Fleming came back to his lab in London. He saw mold growing on a dish of bacteria. Around the mold, the bacteria had died. The mold made something that killed them.

That something became . It was one of the first . An antibiotic is a medicine that kills bacteria or stops them from growing. Penicillin was made in large amounts in the 1940s and saved many lives.

Doctors give antibiotics for infections caused by bacteria, like strep throat. Only a doctor or nurse can decide if you need one. Take it just the way they say, and finish it if they tell you to.

Words to know
antibiotics
medicines that kill bacteria or stop them from growing
penicillin
one of the first antibiotics, first found in a mold
Check yourself

1. Who noticed mold killing bacteria in 1928?

2. What is an antibiotic?

3. Who decides if you need an antibiotic?

9.10

Why Antibiotics Skip Viruses

Main ideaAntibiotics work on bacteria but not on viruses, so they do not help a cold or the flu.

Sam has a runny nose and a cough. He asks his doctor for an antibiotic. The doctor kindly says no. Sam’s cold is caused by a virus, and antibiotics do not work on viruses.

Antibiotics attack parts that bacteria have, like their cell walls. Viruses do not have those parts. So the medicine has nothing to hit. For a cold, rest, fluids and time usually help most.

Using antibiotics when they are not needed can cause a problem. Some bacteria learn to survive them. This is called antibiotic . Using antibiotics only when a doctor says so helps keep them for everyone.

Words to know
resistance
when germs change so a medicine no longer works on them
effective
able to do the job it is supposed to do
Check yourself

1. Why did Sam's doctor not give him an antibiotic?

2. What is antibiotic resistance?

3. What helps most for a cold?

Chapter review

Germs and How We Fight Them

0 / 8

1. Which germs are living cells?

2. Which habit helps stop germs from spreading by touch?

3. What part of the body fights germs with white blood cells?

4. What story gave Edward Jenner his idea?

5. How is a vaccine different from an antibiotic?

6. Which disease was the first ever wiped out worldwide?

7. A fever is best described as what?

8. Why should antibiotics be used only when a doctor says so?

Chapter

First Aid and Emergencies

First Aid
Big questionWhat can a young person do to help when someone is hurt or sick?
The story

Rosa Makes the Call

When her grandfather fell, a ten-year-old girl remembered what to do.

Rosa was doing homework at the kitchen table. Her grandfather was in the next room, reaching for a box on a high shelf. Then she heard a loud thump. She ran in. Grandpa was on the floor. He was awake, but he could not get up, and his arm looked hurt.

Rosa's heart pounded. She wanted to cry. Then she remembered what her teacher had said: take a deep breath first. She breathed in slowly. She told Grandpa, "Stay still. I am getting help." No other grown-up was home.

Rosa picked up the phone and dialed 911. A calm voice asked, "What is your emergency?" Rosa said her grandfather fell and could not get up. She gave her home address, street and number, just the way she had practiced. She answered each question and did not hang up.

The helper on the phone told Rosa to unlock the front door and stay with Grandpa. Soon an ambulance arrived. The paramedics checked Grandpa and took him to the hospital to look at his arm.

Later, Grandpa squeezed Rosa's hand. "You stayed calm," he said. "You knew what to do." Rosa smiled. Knowing her address and practicing the call had made a real difference.

Talk about itWhat did Rosa do first, before she made the call? Why did that help?
Section 1

Caring for Small Hurts

10.1

Cleaning a Small Cut

Main ideaFor a small cut, wash it with clean water, cover it with a bandage and tell an adult.

Jada trips on the sidewalk and scrapes her hand. It stings, and there is a little blood. This is a small cut. Knowing a few steps helps her feel calm. Helping someone with a small hurt is called .

First, wash the cut gently with clean water. Soap around the cut helps too. This rinses out dirt and germs. Next, press with a clean cloth if it is still bleeding. Then cover it with a to keep it clean.

Always tell an adult about a cut. An adult can check it. A cut that is deep, will not stop bleeding, or gets red, puffy and warm later needs a doctor or nurse.

Words to know
first aid
the first help given to someone who is hurt or sick, before a doctor arrives
bandage
a strip or pad that covers a cut to keep it clean
Check yourself

1. What is the first step for a small cut?

2. Why do we cover a cut with a bandage?

3. Which cut needs a doctor or nurse?

10.2

Helping a Nosebleed

Main ideaFor a nosebleed, sit up, lean forward and pinch the soft part of the nose.

Ben is reading when his nose starts to bleed. Nosebleeds happen often, especially when the air is dry. Most stop on their own with the right care. Ben knows what to do.

Ben sits up and leans a little . This keeps blood from running down his throat. He the soft part of his nose, just below the hard bony part. He breathes through his mouth and keeps pinching for about 10 minutes.

Leaning back is an old habit, but it is not the best idea. Blood can go down the throat and upset the stomach. Ben tells an adult. If a nosebleed does not stop or came from a hard hit, an adult should get medical help.

Words to know
forward
toward the front
pinches
presses something tightly between the thumb and finger
Check yourself

1. Which way should you lean for a nosebleed?

2. Where should you pinch?

3. Why is leaning back not a good idea?

10.3

Cooling a Burn

Main ideaFor a small burn, cool it under cool running water and tell an adult; do not use ice or butter.

Mia touches a hot pan by mistake. Her finger turns red and hurts. This is a small . A burn is an injury from heat, like a stove, hot water or the sun.

The first step is to cool the burn. Hold it under for several minutes, until it feels better. Do not use ice. Ice can hurt the skin more. Do not put butter or oil on it either.

Tell an adult right away. An adult can cover a small burn loosely with a clean bandage. A big burn, a burn on the face, or a burn with blisters needs a doctor or nurse.

Words to know
burn
an injury to the skin from heat, fire, hot liquid or the sun
cool running water
water from a faucet that is cool, not icy, used to cool a burn
Check yourself

1. What should Mia do first for her burn?

2. Why not use ice on a burn?

3. Which burn needs a doctor or nurse?

Section 2

Getting Help Fast

10.4

When to Call 911

Main ideaCall 911 when someone is in danger right now, like when they cannot breathe, will not wake up or is badly hurt.

In the United States, 911 is the number to call in an . An emergency is when someone is in danger right now and needs help fast. The call is free from any phone.

Call 911 if someone will not wake up, cannot breathe, is bleeding a lot, or is badly hurt. Call if you see a fire. If a grown-up is nearby, get them first. If not, you can call.

Do not call 911 as a joke or a test. Helpers must be free for real emergencies. The person who answers is a . The dispatcher sends police, firefighters or an ambulance.

Words to know
emergency
a time when someone is in danger and needs help right away
dispatcher
the trained person who answers 911 calls and sends help
Check yourself

1. Which is an emergency?

2. Who answers a 911 call?

3. Why should you never call 911 as a joke?

10.5

What to Say on the Call

Main ideaOn a 911 call, say what happened and where you are, answer the questions and do not hang up until told.

Remember Rosa? When she called, she said what happened: Grandpa fell and could not get up. Then she gave her . An address is the street name and number of a home or building.

Knowing your address is a big help. Practice saying it with a grown-up. If you are not home, look for a street sign or a store name. Say your city too.

Answer each question the dispatcher asks. Speak slowly and clearly. Do not hang up until the dispatcher says you can. The dispatcher may give , like unlocking the door.

Words to know
address
the street number, street name and city of a place
instructions
steps someone tells you to follow
Check yourself

1. What two things should you tell the dispatcher first?

2. What should you do if you are not home and do not know the address?

3. When should you hang up?

10.6

Calling Poison Control

Main ideaIf someone may have swallowed or touched something harmful, an adult can call Poison Control at 1-800-222-1222.

Little Theo finds a bottle under the sink and takes a sip. His big sister sees. She knows cleaners can be harmful. She gets their dad right away. She brings the bottle too.

Dad calls at 1-800-222-1222. That number works across the United States, any time of day or night. Experts there tell callers what to do. A is something that can hurt the body if swallowed, breathed in or touched.

If the person will not wake up or cannot breathe, call 911 instead. To stay safe, never taste things you do not know. Medicines, cleaners and plant sprays should be kept up high or locked away.

Words to know
Poison Control
a free helpline, 1-800-222-1222, with experts who say what to do about poisons
poison
something that can hurt the body if swallowed, breathed in or touched
Check yourself

1. What is the Poison Control number?

2. What did Theo's sister do first?

3. When should you call 911 instead of Poison Control?

Section 3

Allergies and Staying Calm

10.7

What an Allergy Is

Main ideaAn allergy is when the immune system reacts strongly to something that is harmless for most people.

Omar cannot eat peanuts. For most people, peanuts are just a snack. But Omar’s immune system treats peanuts like a germ. This is called an . It is not his fault.

Things that cause allergies are called . Common ones are peanuts, tree nuts, milk, eggs, bee stings and pollen. A mild reaction may be sneezing or an itchy rash.

A very strong reaction is called . The throat may swell, and breathing can get hard. It needs help right away. Friends can help by respecting food rules and never sharing food without asking.

Words to know
allergy
when the immune system reacts strongly to something harmless for most people
allergens
things that can cause an allergy, like peanuts or pollen
anaphylaxis
a very strong allergic reaction that can make breathing hard and needs help right away
Check yourself

1. What is an allergy?

2. Which is a common allergen?

3. What is anaphylaxis?

10.8

Epinephrine Pens

Main ideaAn epinephrine pen is medicine for a severe allergic reaction, used by adults, trained helpers or the person it belongs to.

Some people with serious allergies carry an pen. One well-known brand is the EpiPen. Epinephrine is a medicine that can quickly help with anaphylaxis.

The pen gives a shot, often into the outer thigh. Adults and trained helpers, like school nurses, use it. Some older kids learn to use their own pen with their doctor’s help. After it is used, call 911, because the person still needs a doctor.

Your job as a friend is to know the signs and get an adult fast. Know where your friend’s pen is kept. Never play with someone’s pen. It is real .

Words to know
epinephrine
a medicine that can quickly help during a very strong allergic reaction
medicine
something used to treat or prevent sickness, given the way a doctor says
Check yourself

1. What is an epinephrine pen for?

2. What should happen after an epinephrine pen is used?

3. What is a friend's main job?

10.9

Staying Calm Helps

Main ideaTaking slow breaths helps you think clearly so you can remember the steps and get help.

In an emergency, your heart may race and your hands may shake. That is normal. Your body is getting ready to act. Rosa felt this too when Grandpa fell.

Slow breathing helps. Breathe in through your nose while you count to four. Breathe out slowly. One or two slow breaths help your brain . Then you can remember what to do.

Staying also helps the hurt person. A kind, steady voice helps them feel safe. You can say, "Help is coming. I am here." You do not have to fix everything. Your job is to get help.

Words to know
calm
quiet and steady, not rushed or panicked
focus
to pay attention to one thing
Check yourself

1. Why is it normal for your heart to race in an emergency?

2. What helps you focus in an emergency?

3. What can you say to help a hurt person feel safe?

Section 4

Ready to Help

10.10

A First-Aid Kit

Main ideaA first-aid kit holds supplies for small hurts, and knowing where it is helps you act fast.

Mr. Lopez keeps a red box in his classroom. It has a white cross on it. It is a . Inside are supplies for small hurts. Every student knows where it is.

A kit often has bandages of different sizes, gauze pads, tape, and wipes for cleaning. It may have gloves, a cold pack and small scissors. Homes, schools and cars can each have one.

Know where the kit is kept at home and at school. Check it with a grown-up to replace used . A kit does not replace a doctor. It helps with small things and gets you ready.

Words to know
first-aid kit
a box of supplies for treating small hurts
supplies
things kept ready to be used when needed
Check yourself

1. What is a first-aid kit for?

2. Which item is often in a first-aid kit?

3. Why check the kit with a grown-up?

10.11

Helping a Friend Get an Adult

Main ideaWhen a friend is hurt, one of the best ways to help is to get a trusted adult quickly.

At recess, Lily falls off the monkey bars. She is crying and holding her wrist. Her friend Noah wants to help. He tells her, "Stay here. I will get the recess teacher."

Getting a is often the most important step. A trusted adult is a grown-up you know can help, like a teacher, coach, nurse or parent. Noah does not try to move Lily or fix her arm.

If two friends are there, one can stay while the other runs for help. Tell the adult what happened and where. Being a good means doing your part and letting trained people do theirs.

Words to know
trusted adult
a grown-up you know and can count on for help
helper
someone who does their part to help another person
Check yourself

1. What did Noah do to help Lily?

2. Who is a trusted adult?

3. If two friends are there, what can they do?

Chapter review

First Aid and Emergencies

0 / 8

1. What is the first step for a small cut?

2. For a nosebleed you should…

3. What should you put on a small burn first?

4. What number do you call in a U.S. emergency?

5. What number reaches Poison Control?

6. Who usually uses an epinephrine pen?

7. What helped Rosa think clearly when Grandpa fell?

8. How is a first-aid kit different from a doctor?

Unit wrap-up

Germs, Vaccines and First Aid

Twelve words, twelve meanings

0 / 12

Tap a word, then tap its meaning. A right pair locks in green.

Words
Meanings
Unit test

Fifteen questions across the unit

0 / 15

1. Which germ can only make copies inside a living cell?

2. Which habit best stops germs from spreading by touch?

3. What do white blood cells do?

4. A fever is usually a sign that…

5. What did Edward Jenner use in 1796 to protect against smallpox?

6. How does a vaccine help?

7. In what year was smallpox declared eradicated?

8. Why won't an antibiotic help a cold?

9. Who found that a mold could kill bacteria?

10. What is the first step for a small burn?

11. For a nosebleed, you should…

12. What should you tell a 911 dispatcher first?

13. When might an adult call 1-800-222-1222?

14. Who uses an epinephrine pen?

15. When a friend is hurt at recess, what is one of the best ways to help?

Spiral review

Five questions from earlier units

0 / 5

1. (Unit 4) When you run, why do you breathe faster?

2. (Unit 4) How do germs in the mouth cause cavities?

3. (Unit 4) Which gas do you breathe out as waste?

4. (Unit 4) On a food label, 20 percent Daily Value of a nutrient is usually thought of as...

5. (Unit 4) Which body system includes the brain, spinal cord and nerves?

Write it

Which do you think helps people stay well more: things our bodies do, things scientists discovered, or things we do ourselves? Make a claim. Use two or three facts from the unit to explain your answer.

  • Start with one clear sentence that states your claim.
  • Use unit words like immune system, vaccine or first aid.
  • Name a real example, like Jenner in 1796 or smallpox ending in 1980.
  • Say one good point about a side you did not pick.
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